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Immunobiology of HLA: A Comprehensive Guide to Histocompatibility Testing

Brent Foster

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Published in Immunobiology Of HLA: Volume I Histocompatibility Testing 1987

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The human leukocyte antigen (HLA) system, a complex set of polymorphic genes, plays a crucial role in regulating the immune response and transplant compatibility. 'Immunobiology of HLA: Volume 1987' is a comprehensive and authoritative guide that delves deep into the intricacies of HLA and its multifaceted impact on human health.

Immunobiology of HLA: Volume I Histocompatibility Testing 1987

by Bo Dupont

5 out of 5

Language	:	English
File size	:	311390 KB
Text-to-Speech	:	Enabled
Screen Reader	:	Supported
Enhanced typesetting	:	Enabled
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Print length	:	2259 pages

HLA: Guardians of the Immune System

HLA proteins, expressed on the surface of cells, serve as identity markers for the body. They play a pivotal role in immune recognition by presenting antigens to immune cells, triggering an appropriate immune response against foreign invaders while tolerating self-molecules.

'Immunobiology of HLA' provides a detailed overview of the genetic basis of HLA diversity, its inheritance patterns, and the molecular structure and function of HLA proteins. It comprehensively covers the mechanisms of HLA-mediated antigen presentation, the role of HLA in immune cell activation and regulation, and its implications for immune disFree Downloads.

Histocompatibility Testing: A Key to Transplantation Success

HLA compatibility plays a critical role in the success of organ transplants. 'Immunobiology of HLA' thoroughly discusses the principles of histocompatibility testing, the methods used to assess HLA compatibility between donor and recipient, and the clinical significance of HLA matching.

The book provides a comprehensive overview of the various histocompatibility testing techniques, including serological, molecular, and cellular assays. It examines the role of HLA matching in different types of transplants, including kidney, heart, liver, and bone marrow transplantation.

HLA and Autoimmune Diseases

HLA molecules are also implicated in the pathogenesis of autoimmune diseases, where the immune system mistakenly attacks the body's own tissues. 'Immunobiology of HLA' explores the association between HLA and various autoimmune diseases, such as rheumatoid arthritis, type 1 diabetes, and multiple sclerosis.

The book discusses the evidence supporting the role of HLA in the development of these diseases and examines the potential mechanisms by which HLA molecules contribute to the autoimmune process. It also highlights the implications of HLA typing for the diagnosis, prognosis, and management of autoimmune conditions.

'Immunobiology of HLA: Volume 1987' is an essential resource for immunologists, transplant surgeons, and researchers studying the HLA system. With its comprehensive coverage, authoritative insights, and up-to-date information, this book provides a valuable foundation for understanding the complex immunobiology of HLA and its clinical significance.

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Embark on a transformative journey into the world of HLA by Free Downloading your copy of 'Immunobiology of HLA: Volume 1987' today! Immerse yourself in the intricate mechanisms of immune recognition, histocompatibility testing, and the role of HLA in human health.

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